532 nm
Laser Line
ER Probes MarkER-ROS
The ER is composed of rough and smooth domains. Accumulation of unfolded or misfolded proteins results in ER stress, which can lead to a variety of health conditions including tumorigenesis, neurodegenerative diseases, and diabetes. As such, the ER is an excellent molecular target for PDT. Excessive ER stress has been linked to immunogenic cancer cell death (ICD) resulting from damage associated molecular patterns (DAMPs). ER stress can be triggered by excess ROS; however, given the short half-life of 1O2 (<300 ns) this strategy for cancer therapy requires developing bimodal PS’s capable of ER-localization along with light driven 1O2 production.
| Catalog Number | Unit Size | Price (USD) | Availability | Quantity |
|---|---|---|---|---|
| MarkER-ROS-0.5 | 0.5 mg | $250.00 | In Stock | |
| MarkER-ROS-1 | 1 mg | $350.00 | In Stock |
Cy3
Common Filter Set
554 nm
Excitation Max
600 nm
Emission Max
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